Learning in Aplysia

June 29, 2000
From: Raphaël Favre

Dear professor,

My name is Raphaël Favre and I'm a student in biochemistry at the Univerity of Geneva in Switzerland. I've to do a study about long-term facilitation in Aplysia. Could you please recommand me any articles that treat about the enzymatic mechanisms of LTP ?

I thank you a lot, your web site is really great,

Raphaël

pharias@hotmail.com

Favre, R., 2000 (Jun 29) Learning in Aplysia. [Message in] Sea Slug Forum. Australian Museum, Sydney. Available from http://www.seaslugforum.net/find/2616

Dear Raphaël,
I appreciate your thought that I can answer any question on Sea Hares, but the truth is that although research on how brains work fascinates me, I must admit I have no time to keep up with it. I have relied on the comprehensive, but somewhat dated reviews of Kandel, which I have referred to in an earlier message, and the occasional article in magazines such as Science. To those of you who at a complete loss with the question, LTP or long term potentiation is a name for a process that increases the strength of the synaptic connections between neurons. In one model of how memory and learning works it is thought that 'learning' is the result of the build up of specific synaptic connections or pathways between neurons and through the accumulation of such connections, brains learn things and memories develop.

As I've have said elsewhere in the Forum, Aplysia, with a relatively simple nervous system and large nerve cells has proved an ideal animal for use in the study of learning.

Unfortunately Raphaël, I can't help with any recent reviews on the subject. If you find one, could you let me know so I can add it to the Forum. Or perhaps when you finish your review you could write us a summary on the subject, remembering of course that most of us have never developed neural pathways to deal with this area of science.

Best wishes,
Bill Rudman.

Rudman, W.B., 2000 (Jun 29). Comment on Learning in Aplysia by Raphaël Favre. [Message in] Sea Slug Forum. Australian Museum, Sydney. Available from http://www.seaslugforum.net/find/2616

Factsheet

What are Sea Hares? - page 2

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