Dolabella auricularia - source of new drug

February 24, 2001
From: Arnaud Parenty

Hello
It's the first time, I've written to this kind of website. I am doing a Ph D in chemistry in France and I am working on substances extracted from Dolabella auricularia. I want just to say that this Sea Hare is a source for new drugs called dolastatines. These substances discovered by Pettit and coworkers (Pettit, G. 1993; Tetrahedron, Vol 41, p9151) have a great potential to cure cancer.

Actually, two of those products are in clinical trial. For an extensive review about dolastatines, you can read this article:
Current Pharmaceutical Design 1999 Vol 5, N°3, pages 139-162

I hope I have contributed to your great web site. I am a French diver too. I have sent a photo of Dondice banyulensis separately.
Best regards
Arnaud Parenty

arnaud.parenty@icsn.cnrs-gif.fr

Parenty, A., 2001 (Feb 24) Dolabella auricularia - source of new drug. [Message in] Sea Slug Forum. Australian Museum, Sydney. Available from http://www.seaslugforum.net/find/3859

Dear Arnaud,
Welcome to the Forum, and thanks for the information on Dolabella.
Bill Rudman

Factsheet

Dolabella auricularia

Related messages

  1. Re: Suitability of Dolabella auricularia in an aquarium
    From: Jorgen Svard, March 8, 2010
  2. Dolabella auricularia diet
    From: Keith Teller, November 16, 2009
  3. Re: Dolabella auricularia from Tonga
    From: Alastair Robertson, October 13, 2009
  4. Re: Marine Spaghetti from the Philippines
    From: Lorraine M. Cueva, September 25, 2009
  5. Unknown from Camden Haven, New South Wales
    From: Samson Kwok, January 9, 2009
  6. Dolabella auricularia from Mozambique
    From: Valda Fraser, April 14, 2008
  7. Sea hare from Port Hacking, Sydney
    From: David Robertson, April 7, 2008
  8. Dolabella from South Africa
    From: Waldo Nell, August 16, 2006
  9. Re: Lukot - Marine Spaghetti from the Philippines
    From: Richard Parker, August 3, 2006
  10. Lukot - Marine Spaghetti from the Philippines
    From: Richard Parker, August 1, 2006
  11. Is Dolabella auricularia hermaphrodite?
    From: Gary Majchrzak, July 10, 2006
  12. Dolabella auricularia from Forster, NSW.
    From: Colin Malakou, March 23, 2006
  13. Re: Is my sea hare sick?
    From: Brian Vastag, July 19, 2005
  14. Dolabella auricularia from Sth Korea
    From: Dong Bum Koh, July 18, 2005
  15. Is my sea hare sick?
    From: Brian Vastag, July 18, 2005
  16. Dolabella auricularia from Natal
    From: Gerda du Raan, June 6, 2005
  17. Dolabella auricularia in aquarium
    From: Tomoko Schum, February 8, 2005
  18. Sea Hare from Hawaii
    From: Lyudmila Zinkova , December 23, 2004
  19. Dolabella auricularia from Sydney Harbour
    From: Greg Braun, August 11, 2004
  20. Re: Sea Hares
    From: Tom and Jack Burrows, February 4, 2004
  21. Sea slugs?
    From: Tom and Jack Burrows, February 3, 2004
  22. Dolabella auricularia from Red Sea
    From: Isabelle Drouet, January 22, 2004
  23. Suitability of Dolabella auricularia in an aquarium
    From: Carolyn Bryce, December 6, 2003
  24. Inking behavior in Dolabella auricularia
    From: Jaron Brown, October 3, 2003
  25. Dolabella auricularia in the South China Sea
    From: Kheong San Chang, April 17, 2003
  26. Re: Dolabella - Captive breeding
    From: Cathryn Clarke, March 31, 2003
  27. Dolabella auricularia captive breeding
    From: Hervé, March 29, 2003
  28. Dolabella auricularia from the Philippines
    From: Anevi Gunday, February 6, 2003
  29. Dolabella auricularia from Lord Howe Island
    From: W.B. Rudman, January 30, 2003
  30. Dolabella auricularia and egg masses
    From: Rachel Przeslawski, January 14, 2003
  31. Re: Growth stages in Dolabella auricularia
    From: Alicia Hermosillo, January 4, 2003
  32. Re: Growth stages in Dolabella auricularia
    From: Alicia Hermosillo, January 2, 2003
  33. Re: Dolabella juveniles
    From: Mary Jane Adams, January 2, 2003
  34. Growth stages in Dolabella auricularia
    From: Mary Jane Adams , January 1, 2003
  35. Dolabella auricularia in the Philippines
    From: Jonathan P. Ubaldo, December 5, 2002
  36. EU survey of Dolabella
    From: Kim Friedman , September 23, 2002
  37. Aplysiid from Bahia de Banderas
    From: Alicia Hermosillo, September 13, 2002
  38. About dolastatines
    From: Denis Berlemont, July 6, 2002
  39. Dolabella auricularia from Sth Korea
    From: Dong Bum, Koh, June 28, 2002
  40. Natural history of Dolabella auricularia
    From: Sheena, March 5, 2002
  41. Dolabella auricularia from Japan
    From: Nishina Masayoshi , November 5, 2001
  42. Where can we find Dolabella
    From: T. Thiru, September 15, 2001
  43. Chemical defense in Dolabella
    From: Julia Brooke, April 8, 2001
  44. Diet of Dolabella auricularia
    From: Arnaud Parenty, March 28, 2001
  45. Re: Dolabella auricularia and burrowing
    From: Don Barclay, March 19, 2001
  46. Dolabella auricularia and burrowing
    From: Don Barclay, March 17, 2001
  47. Re: Sea Hare eggs
    From: Nerissa Bontia, October 14, 2000
  48. Dolabella auricularia from Solomon Ids
    From: Bruce Potter, October 13, 2000
  49. Aplysiid egg compounds
    From: Kirsten Benkendorff, September 22, 2000
  50. Sea Hare eggs
    From: Nerissa Bontia, September 21, 2000
  51. Re: Dolabella as food
    From: Claudia Armann, July 23, 1999
  52. Dolabella auricularia research
    From: Sandeep K. Singh, June 22, 1999
  53. Dolabella egg masses
    From: Erwin Koehler, April 1, 1999
  54. Re:Dolabella in Fiji - as food etc
    From: Veikila Vuki, March 17, 1999
  55. Re:Dolabella research in Fiji
    From: Sandeep K. Singh, March 16, 1999
  56. Re: Dolabella in Fiji
    From: Sandeep K. Singh, March 16, 1999
  57. Dolabella research in Fiji
    From: Dr. Veikila Vuki, March 10, 1999

Show factsheet and all related messages